1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester

1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester - Names and Identifiers

Name	5-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms	AKOS B024669 ART-CHEM-BB B024669 TIMTEC-BB SBB009683 3-(Methoxycarbonyl)-5-phenyl-1H-pyrazole Methyl 5-phenyl-1H-pyrazole-3-carboxylate 5-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester 3-(Methoxycarbonyl)-5-phenyl-1H-pyrazole, [3-(Methoxycarbonyl)-1H-pyrazol-5-yl]benzene
CAS	56426-35-8

1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester - Physico-chemical Properties

Molecular Formula	C11H10N2O2
Molar Mass	202.21
Melting Point	180～182℃
Storage Condition	2-8°C

1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester - Risk and Safety

Hazard Symbols

Xi - Irritant

1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester - Upstream Downstream Industry

Downstream Products

1-METHYL-3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID

1H-Pyrazole-3-carboxylic acid, 5-phenyl-, Methyl ester - Introduction

Methyl 5-phenyl-1H-pyrazole-3-carboxylate is an organic compound with the following properties:

Appearance: Colorless or light yellow liquid
Molecular formula: C11H10N2O2
Molecular weight: 198.21g/mol
Melting point: 52-55 ° C
Boiling point: 321-322 ° C
Solubility: Soluble in common organic solvents such as ether and dichloromethane

5-Phenyl-1H-pyrazole-3-carboxylic acid methyl ester is commonly used for the following:

1. As a drug intermediate: can be used to synthesize a variety of biologically active compounds. For example, it can be used as an important intermediate in the synthesis of anticancer drugs, antiviral drugs and antibacterial drugs.

2. As pesticide intermediates: can be used to synthesize pesticides such as pesticides and herbicides. It can provide the basic skeleton of different compounds, with insecticidal and herbicidal activity.

The method for preparing 5-phenyl-1H-pyrazole-3-carboxylic acid methyl ester can be through the following reaction steps:

1. First, phenylacetone is reacted with hydrazide to generate 2-phenylpyrazole.

2. Then, 2-phenyl pyrazole and methyl cyanoacetate are reacted to generate methyl 5-phenyl -1H-pyrazole-3-carboxylate.

When using 5-phenyl-1H-pyrazole-3-carboxylic acid methyl ester, you need to pay attention to its safety information:

1. It is an organic compound and belongs to hazardous chemicals. Care should be taken to avoid contact with skin and inhalation of gases during handling and storage.

2. Use the need to wear personal protective equipment, such as gloves and protective glasses.

3. Store in a sealed container and avoid contact with oxidants and strong acids in the air.

4. Toxic gases may be produced when reacting with other chemical substances, so avoid mixing with strong oxidants and strong acids.

Please note that when using any chemicals, you should follow the correct safety procedures, and conduct further research and experiments as needed.

Last Update：2024-04-09 21:21:28